2 Timothy 4:19
(19) Salute Prisca and Aquila.--These were two of St. Paul's earliest friends after he had begun his great work for his Master. Originally of Pontus, they had taken up their abode at Rome, where Aquila exercised his trade of a tent-maker.

Driven out of Rome by the decree of Claudius, which banished the Jews from the capital, they came to Corinth, where St. Paul became acquainted with them. But they were evidently Christians when St. Paul first met them, about A.D. 51-2. We hear of them in company with St. Paul at Corinth, about A.D. 52-3 (Acts 18:2); at Ephesus, about A.D. 55 (1Corinthians 16:19); and in the year A.D. 58 St. Paul sends greetings to them at Rome (Romans 16:3).

They were, evidently, among the many active and zealous teachers of the first days of the faith. That they possessed great ability as well as zeal is evident from the fact that it was from them that the eloquent and trained Alexandrian master, Apollos, learnt to be a Christian (Acts 18:26). In this place, and in several other passages, Prisca (or Priscilla) is named before her husband, Aquila. This would seem to hint that in this case the woman was the principal worker of the two in the cause of Christ. She, in fact, was one of that band of devoted holy women which the preaching of Christ and His disciples had called into existence: a representative of the great class of noble female workers which had no existence before Christ told the world what was the true position of women--until the same divine Master taught them that they, too, as well as men, had a work to work for Him here.

And the household of Onesiphorus.--St. Paul may have been aware that Onesiphorus was absent then from Ephesus; but this peculiar greeting, taken together with the words of 2Timothy 1:16, leads us irresistibly to the conclusion that this friend of St. Paul's was dead when the Epistle was written. (See Notes on 2Timothy 1:16.)

Verse 19. - House for household, A.V. Prisca and Aquila. Prisca is elsewhere always called Priscilla (Acts 18:2, 18, 26; Romans 16:3; 1 Corinthians 16:19). A similar variation of names is seen in Drusa and Drusilla, Livia and Livella, etc. She is named before her husband, as here in Acts 18:18; Romans 16:3. The mention of them here is in favour of Timothy being at Ephesus at this time, as Ephesus is one of the places where they were wont to sojourn (Acts 18:19, 26). The house (as in A.V. ch. 1:16) of Onesiphorus (see ch. 1:16, 18, note). This repetition of the "house of Onesiphorus" is almost conclusive as to the recent death of Onesiphorus himself.

4:19-22 We need no more to make us happy, than to have the Lord Jesus Christ with our spirits; for in him all spiritual blessings are summed up. It is the best prayer we can offer for our friends, that the Lord Jesus Christ may be with their spirits, to sanctify and save them, and at last to receive them to himself. Many who believed as Paul, are now before the throne, giving glory to their Lord: may we be followers of them.Salute Prisca and Aquila,.... The same with Priscilla and Aquila: and so the Complutensian edition, and some copies, read here; who were of the same occupation with the apostle, and with whom he wrought at Corinth, and whom he left at Ephesus; and who seem by this salutation to have continued there, Acts 18:2.

And the household of Onesiphorus: who also lived at Ephesus, and whose kindness to the apostle, when he was at Rome, is before mentioned, 2 Timothy 1:16.

2 Timothy 4:18
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